New Perspectives in Clinical Trials

Prof. Stefano Bonassi, Ph.D., ERT, Department of Human Sciences and Quality of Life Promotion, San Raffaele University, Head of the Unit of Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Italy

Date: 15.6.2022 at 14:00 (CET)

Clinical trials are our best approach to generate clinical evidence. Since the early stages in the first decades of the past century, clinical trial has been in continuous evolution. Innovation has interested the formulation of stopping guidelines for safety, efficacy, and futility; the use of internet, changes in the way the informed consent is requested, the introduction of pragmatic trials, the challenge of personalized medicine, the concept of non-inferiority, and many others. Today, trials range from a single person to hundred-thousand people, from a single lab to hundreds of centers around the world, from simple two-arm randomizations to increasingly complex study designs. The lecture will address issues related to the performance of clinical trials, how to deal with the increasing use of the internet, the dramatic change concerning ethics in clinical studies.